SYNTHESIS OF THREE NEW BIFUNCTIONAL GLUCOSE-THIOUREA ORGANOCATALYSTS AND THEIR APPLICATION IN ASYMMETRIC MICHAEL ADDITION
| dc.contributor.author | Sándor NAGY | |
| dc.contributor.author | Petra KOZMA | |
| dc.contributor.author | Péter KISSZÉKELYI | |
| dc.contributor.author | Dóra BEZZEGH | |
| dc.contributor.author | Péter HUSZTHY | |
| dc.contributor.author | József KUPAI | |
| dc.date.accessioned | 2024-10-17T11:29:08Z | |
| dc.date.issued | 2017-03-30 | |
| dc.description | STUDIA UBB CHEMIA, LXII, 1, 2017 (p. 183-194), DOI:10.24193/subbchem.2017.1.16 Sándor NAGY Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Budapest, Hungary, nagy.sandor@mail.bme.hu https://orcid.org/0000-0001-6251-5382 Petra KOZMA Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Budapest, Hungary Péter KISSZÉKELYI Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Budapest, Hungary, pkisszekelyi@mail.bme.hu https://orcid.org/0000-0002-9529-0674 Dóra BEZZEGH Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Budapest, Hungary Péter HUSZTHY Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Budapest, Hungary, huszthy@mail.bme.hu https://orcid.org/0000-0002-3652-9892 József KUPAI Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Budapest, Hungary *Corresponding author: jkupai@mail.bme.hu https://orcid.org/0000-0002-4212-4517 | |
| dc.description.abstract | Three new glucose-based asymmetric bifunctional organocatalysts containing a 6-aminopyridyl or a 6-methylpyridyl or a cinchona unit were synthesized. Asymmetric Michael addition of pentane-2,4-dione to β-nitrostyrene was catalyzed successfully by these catalysts. In case of the cinchona based glucose-thiourea derivate the S enantiomer of the corresponding Michael adduct was formed with moderate enantiomeric excess in three different solvents. | |
| dc.description.sponsorship | The financial support of the Hungarian Scientific Research Fund/ National Research, Development and Innovation Office, Hungary (OTKA/ NKFIH Nos. K 112289 and PD 108462) is gratefully acknowledged. | |
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| dc.identifier.issn | 1224-7154 | |
| dc.identifier.issn | (online): 2065-9520 | |
| dc.identifier.uri | http://dspace.chem.ubbcluj.ro:4000/handle/20.500.14637/49 | |
| dc.language.iso | en | |
| dc.publisher | STUDIA UBB CHEMIA. Published by Babeş-Bolyai University | |
| dc.relation.ispartofseries | STUDIA UBB CHEMIA, LXII, 1, 2017 (p. 183-194), DOI:10.24193/subbchem.2017.1.16 | |
| dc.subject | organocatalyst | |
| dc.subject | carbohydrates | |
| dc.subject | cinchona alkaloids | |
| dc.subject | Michael addition | |
| dc.subject | asymmetric syntheses | |
| dc.title | SYNTHESIS OF THREE NEW BIFUNCTIONAL GLUCOSE-THIOUREA ORGANOCATALYSTS AND THEIR APPLICATION IN ASYMMETRIC MICHAEL ADDITION | |
| dc.type | Article |