PRACTICAL INVESTIGATION OF GELS CONTAINING ARISTOLOCHIA (ARISTOLOCHIA CLEMATITIS) EXTRACT

dc.contributor.authorPaul ATYIM
dc.contributor.authorNeli-Kinga OLAH
dc.contributor.authorGyöngyi OSSER
dc.contributor.authorClaudia-Crina TOMA
dc.contributor.authorClaudiu MORGOVAN
dc.contributor.authorElisabeta ATYIM
dc.date.accessioned2024-10-17T11:03:14Z
dc.date.issued2017-03-30
dc.descriptionSTUDIA UBB CHEMIA, LXII, 1, 2017 (p. 153-164), DOI:10.24193/subbchem.2017.1.13 Paul ATYIM Department of Pharmaceutical Sciences, Faculty of Pharmacy, Vasile Goldis Western University, Arad, Romania, dpatyim@yahoo.co.uk Neli-Kinga OLAH Faculty of Pharmacy, Vasile Goldiș Western University, Arad; SC PlantExtrakt SRL, Rădaia, Cluj, Romania https://orcid.org/0000-0001-5204-6885 Gyöngyi OSSER Department of Pharmaceutical Sciences, Faculty of Pharmacy, Vasile Goldis Western University, Arad, Romania https://orcid.org/0009-0007-8181-4581 Claudia-Crina TOMA Faculty of Pharmacy, Vasile Goldiș Western University, Arad, Romania, claudiatoma2004@yahoo.com https://orcid.org/0000-0003-1515-3256 Claudiu MORGOVAN Department of Pharmaceutical Sciences, Faculty of Pharmacy, Vasile Goldis Western University, Arad, Romania, claudiumorgovan@yahoo.com https://orcid.org/0000-0003-2730-8729 Elisabeta ATYIM Kölcsey Ferenc National College, Satu Mare, Romania. * Corresponding authors: dpatyim@yahoo.co.uk, claudiumorgovan@yahoo.com
dc.description.abstractThe aim of this study is to embed the active ingredients of the hydroalcoholic extract from the aristolochia (Aristolochia clematitis) into a new semisolid preparation and a viscoelastic methylcellulose based hydrogel in order to broaden the topical applicability of the palette’s range. The methylcellulose based hydroalcoholic gel formulation, preparation and quality evaluation was realized by continuously measuring the product’s physico-chemical parameters. The evaluated physico-chemical parameters: the swelling degree, the equilibrium swelling degree, the swelling rate and the swelling fraction, the swelling rate parameter, the swelling kinetics order, the speed constant.
dc.identifier.citationLavinia Vlaia, Ioana Olariu, Georgeta Coneac, Ana Maria Muţ, V. Vlaia, Z. Szabadai, D. Lupuleasa, Practica farmaceutica, 2015, 8, 5. N.A. Peppas, P. Bures, W. Leobandung, H. Ichikawa, European Journal of Pharmaceutics and Biopharmaceutics, 2000, 50, 27. J. Siepmann, R. Siegel, M. Rathbone, Fundamentals and Applications of Controlled Release Drug Delivery, Eds. Spinger, New York, NY, 2012, 75. Iuliana Popovici, D. Lupuleasa, Tehnologie farmaceutică, Eds. Polirom, 2008, Tom 2, 1500. D. Košťálová, V. Hrochová, N. Pronayová, J. Leško, Chemical Papers, 1991, 45 (5), 713. Heinrich, M., Chan, J., Wanke, S., Neinhuis, C., & Simmonds, M.S., Journal of Ethnopharmacology, 2009, 125 (1), 108. Camelia Papuc, Maria Crivineanu, G. Goran, V. Nicorescu, Nicoleta Durdun, Revista de Chimie, 2010, 61, 7, 619. Laura Vicaş, Practica farmaceutică, 2012, 5, 23. A. Barati, H. Norouzi, S. Sharafoddinzadeh, R. Davarnejad, World Applied Sciences Journal, 2010, 11 (11): 1336. A.S. Kipcak, O. Ismail, I. Doymaz, S. Piskin, Journal of Chemistry, 2014, Volume 2014, Article ID 281063, 8 pages. M. Sadeghi, G. Koutchakzadeh, Journal of Sciences (Islamic Azad University), 2007, 17, 19. J.R. Quintana, N.E. Valderruten, I. Katime, Langmuir, 1999, 15, 4728. F. Ganji, S. Vasheghani-Farahani, E. Vasheghani-Farahani, Iranian Polymer Journal, 2010, 19 (5), 375. G.W. Davidson, N.A. Peppas, Journal of Controlled Release, 1986, 3, 243. Ch. Chang, B. Duan, J. Cai, L. Zhang, European Polymer Journal, 2010, 46, 92. Elena Dinte, M. Todica, C.V. Pop, S. E. Leucuta, Studia UBB Physica, 2008, LIII, 55. A. Kostić, B. Adnadjević, A. Popović, Jelena Jovanović, Journal of the Serbian Chemical Society, 2007, 72 (11), 1139. *** Romanian Pharmacopoeia X (RP X), Eds. Editura Medicală, Bucuresti, 1993, 1315.
dc.identifier.issn1224-7154
dc.identifier.issn(online): 2065-9520
dc.identifier.urihttp://dspace.chem.ubbcluj.ro/handle/20.500.14637/46
dc.language.isoen
dc.publisherSTUDIA UBB CHEMIA. Published by Babeş-Bolyai University
dc.relation.ispartofseriesSTUDIA UBB CHEMIA, LXII, 1, 2017 (p. 153-164), DOI:10.24193/subbchem.2017.1.13
dc.subjectAristolochia clematitis
dc.subjecthydrogel
dc.subjectmethylcellulose
dc.subjectpH
dc.subjectswelling parameters
dc.titlePRACTICAL INVESTIGATION OF GELS CONTAINING ARISTOLOCHIA (ARISTOLOCHIA CLEMATITIS) EXTRACT
dc.typeArticle

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